Gene therapy in inherited blood disorders: A spotlight on sickle cell disease and beta‑thalassaemia

  Inherited blood disorders are a group of conditions that alter the production, structure or function of blood cells, often requiring coordinated long-term management of patients. Haemoglobinopathies represent a subgroup of inherited blood disorders characterised by genetic changes in the haemoglobin, a key protein in the blood responsible for oxygen transport. Sickle cell disease (SCD) and beta-thalassaemia are two …